USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: G3BP1_HUMAN USC-OGP 2-DE database:  G3BP1_HUMAN G3BP1_HUMAN General information about the entry View entry in simple text format Entry name G3BP1_HUMAN Primary accession number Q13283 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12; EC=3.6.4.13; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;. Gene name Name=G3BP1 Synonyms=G3BP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1312: pI=5.04; Mw=21529 Cross-references UniProtKB/Swiss-Prot Q13283; G3BP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name G3BP1_HUMAN Primary accession number Q13283 Secondary accession number(s) Q5HYE9 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 178) Name and origin of the protein Description RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12; EC=3.6.4.13; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1; Gene name Name=G3BP1 Synonyms=G3BP Encoded on Name=G3BP1; Synonyms=G3BP Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; DNA-binding; Endonuclease; Helicase; Hydrolase; Membrane; Methylation; Nuclease; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U32519; AAB07787.1; -; mRNA EMBL AK300098; BAG61899.1; -; mRNA EMBL BX647869; CAI46065.1; -; mRNA EMBL AC091982; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC006997; AAH06997.1; -; mRNA CCDS CCDS4319.1; -. [Q13283-1]; . RefSeq NP_005745.1; NM_005754.2. [Q13283-1]; . RefSeq NP_938405.1; NM_198395.1. [Q13283-1]; . RefSeq XP_006714812.1; XM_006714749.3. [Q13283-1]; . RefSeq XP_006714813.1; XM_006714750.3. [Q13283-1]; . RefSeq XP_016864411.1; XM_017008922.1. [Q13283-1]; . RefSeq XP_016864412.1; XM_017008923.1. [Q13283-1]; . UniGene Hs.3353; -; . UniGene Hs.587054; -; . PDB 3Q90; X-ray; 1.70 A; A/B=1-139 PDB 4FCJ; X-ray; 1.62 A; A/B=1-139 PDB 4FCM; X-ray; 2.69 A; A/B=1-139 PDB 4IIA; X-ray; 3.30 A; A=11-139 PDB 5FW5; X-ray; 1.92 A; A/B=1-139 PDBsum 3Q90; -; . PDBsum 4FCJ; -; . PDBsum 4FCM; -; . PDBsum 4IIA; -; . PDBsum 5FW5; -; . ProteinModelPortal Q13283; -; . SMR Q13283; -; . BioGrid 115448; 123; . IntAct Q13283; 76; . MINT MINT-5002789; -; . STRING 9606.ENSP00000348578; -; . iPTMnet Q13283; -; . PhosphoSitePlus Q13283; -; . SwissPalm Q13283; -; . BioMuta G3BP1; -; . DMDM 14916572; -; . EPD Q13283; -; . PaxDb Q13283; -; . PeptideAtlas Q13283; -; . PRIDE Q13283; -; . DNASU 10146; -; . Ensembl ENST00000356245; ENSP00000348578; ENSG00000145907. [Q13283-1]; . Ensembl ENST00000394123; ENSP00000377681; ENSG00000145907. [Q13283-1]; . Ensembl ENST00000520177; ENSP00000427810; ENSG00000145907. [Q13283-2]; . Ensembl ENST00000522367; ENSP00000428926; ENSG00000145907. [Q13283-2]; . GeneID 10146; -; . KEGG hsa:10146; -; . UCSC uc063iwq.1; human. [Q13283-1]; . CTD 10146; -; . DisGeNET 10146; -; . GeneCards G3BP1; -; . HGNC HGNC:30292; G3BP1; . HPA CAB037068; -; . HPA HPA004052; -; . MIM 608431; gene; . neXtProt NX_Q13283; -; . OpenTargets ENSG00000145907; -; . PharmGKB PA162389105; -; . eggNOG KOG0116; Eukaryota; . eggNOG ENOG410YV57; LUCA; . GeneTree ENSGT00390000011365; -; . HOGENOM HOG000220838; -; . HOVERGEN HBG007211; -; . InParanoid Q13283; -; . KO K17265; -; . OMA IMRNNAG; -; . OrthoDB EOG091G0GAN; -; . PhylomeDB Q13283; -; . TreeFam TF325464; -; . ChiTaRS G3BP1; human; . GeneWiki G3BP1; -; . GenomeRNAi 10146; -; . PRO PR:Q13283; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000145907; -; . CleanEx HS_G3BP1; -; . ExpressionAtlas Q13283; baseline and differential; . Genevisible Q13283; HS; . GO GO:0010494; C:cytoplasmic stress granule; IEA:Ensembl; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0030529; C:intracellular ribonucleoprotein complex; IBA:GO_Central; . GO GO:0005634; C:nucleus; TAS:ProtInc; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc; . GO GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc; . GO GO:0003677; F:DNA binding; IEA:UniProtKB-KW; . GO GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW; . GO GO:0003729; F:mRNA binding; IBA:GO_Central; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl; . GO GO:0007265; P:Ras protein signal transduction; TAS:ProtInc; . GO GO:0006810; P:transport; IEA:UniProtKB-KW; . CDD cd00780; NTF2; 1; . Gene3D 3.10.450.50; -; 1; . Gene3D 3.30.70.330; -; 1; . InterPro IPR002075; NTF2; . InterPro IPR032710; NTF2-like_dom; . InterPro IPR018222; Nuclear_transport_factor_2_euk; . InterPro IPR012677; Nucleotide-bd_a/b_plait; . InterPro IPR000504; RRM_dom; . Pfam PF02136; NTF2; 1; . Pfam PF00076; RRM_1; 1; . SMART SM00360; RRM; 1; . SUPFAM SSF54427; SSF54427; 1; . SUPFAM SSF54928; SSF54928; 1; . PROSITE PS50177; NTF2_DOMAIN; 1; . PROSITE PS50102; RRM; 1; .

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